DNA Extraction and Shotgun Metagenomics Sequencing of Fecal Samples
Contact and place of performance
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Bethesda, MD 20892
USA
This is a Notice of Intent, not a request for proposal. The National Institute of Health intends to negotiate on an other than full and open competition basis with the following vendor: Rush University Medical Center. Acquisition Description: This acquisition requested is for DNA extraction and shotgun metagenomics sequencing of fecal samples from humans (n=25) at baseline and after a ketogenic diet with/with N...
View moreAll responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.
The National Institutes of Health intends to negotiate a sole source contract with Rush University Medical Center for DNA extraction and shotgun metagenomics sequencing of fecal samples. This acquisition, identified under solicitation number NOI-CC-OLAO-26-00551, supports research to understand cross-species validation of mechanisms related to bile acid- and FXR-induced increases in ketogenesis. The required services involve processing 200 total samples, including 100 human samples collected at baseline and following a ketogenic diet with or without NR supplementation, as well as 100 mouse samples collected at baseline and following a high-fat diet with or without NR supplementation. The vendor will perform DNA extraction, library preparation, and shotgun metagenomics sequencing, subsequently providing the raw data files to the Principal Investigator in Bethesda, Maryland.
This requirement is classified under NAICS code 622110 for General Medical and Surgical Hospitals and PSC code Q301 for Medical Laboratory Testing. There is no set-aside designated for this procurement, as the government intends to award the contract under the authority of FAR 6.302-1, which applies when only one responsible source can satisfy agency requirements. While this notice of intent is not a request for proposal, responsible sources may submit capability statements for consideration by 12:00 PM Eastern Standard Time on May 23, 2026. The procurement documentation includes two attachments: a statement of work and a price quote.
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